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Acid reflux on a GLP-1? 5 things I tell every patient.
Ozempic, Wegovy, Mounjaro, Zepbound. If you take a GLP-1 and now have heartburn, sulfur burps and bad nights, start here.
You started a GLP-1. The weight is finally coming off. Then this started:
- Acid reflux and heartburn, often right after a dose increase
- Waking up at 2 or 3am with acid in your throat
- Sleeping propped up, or on the couch
- Food sitting in your stomach for hours
- Sulfur burps that taste like rotten eggs
- Bloating and a heavy, too-full stomach after a normal meal
- Tums, Pepcid, even omeprazole, and still burning
Acid reflux is one of the most common GLP-1 side effects. You're not imagining it. And you're not doing anything wrong.
1. Keep taking your GLP-1.
This is the first thing I say, because it's the first thing you're scared of.
Your GLP-1 is working. Acid reflux is not a reason to stop it. My job is to help you stay on it comfortably.
2. GLP-1 reflux is not an acid problem. It's a direction problem.
GLP-1 medications like Ozempic and Mounjaro slow down how fast your stomach empties. That's on purpose. It's why you feel full on half a plate.
But food that sits in your stomach longer has more time to push back up. Especially when you lie down.
That's the 3am acid. That's the sulfur burps. That's the bloating. Food that should go down is going up.
It's in the research: a 2025 review of 55 trials and more than 106,000 people found GLP-1 medications probably raise the risk of acid reflux.
| What it does | Moves food down? | |
|---|---|---|
| Tums | Neutralizes acid | No |
| Pepcid, omeprazole | Makes less acid | No |
| Gaviscon | Puts a lid on it | No |
3. Why Tums, Pepcid and omeprazole don't fix GLP-1 reflux.
They all work on acid. None of them works on direction. Your GLP-1 is still slowing your stomach down.
That's why you can take all of them and still wake up with acid in your throat.
4. What I give my GLP-1 patients instead.
Liao. I made it for my dad, who lived with heartburn for 30 years. Today it's what I give patients with GLP-1 reflux.
It's based on a Chinese formula written down about 1,800 years ago for exactly this: a stomach that pushes up when it should move down. It was written for that heavy, too-full feeling and, word for word, belching that won't stop.
Three herbs, one job each:
- Inula flower sends food back down.
- Hematite settles what keeps coming up.
- Licorice root soothes the burn in your throat and chest.
Plus a prebiotic. No sugar, which matters if you take a GLP-1 for your blood sugar. One small spoon, 30 minutes before breakfast and dinner.
Before launch, we followed 30 people through 90 days of Liao, taken daily alongside the lifestyle guidance in Dr. Lyda Kermani's TCM Digestion Guide, included with every order. By the end of month three, 86% reported less reflux. More than half felt good enough to move to maintenance use: keeping Liao for bigger meals, travel, and the days they know will be heavy.
The test ran 90 days for a reason. That is the timescale we trust.
A small internal test of 30 people, not a clinical trial. Individual experiences vary.
30-day money-back guarantee
- The first spoon Warm and soothing going down. Your stomach feels calmer, not heavy.
- Week 1 Fewer sulfur burps. Less bloating. Food stops sitting in your stomach.
- Weeks 2 to 3 Fewer 3am wake-ups with acid. The Tums stay in the drawer.
- Week 8 Dinner at a normal time. The whole night, flat, in your own bed.
5. What you'll feel, and when.
Keep taking your GLP-1 exactly as prescribed. Tell your prescriber you're adding Liao. That's it.
Quick answers
Can I take Liao with Ozempic, Wegovy, Mounjaro or Zepbound?
Yes. On a weekly GLP-1 injection, there's no special timing. On a GLP-1 tablet like Rybelsus, take the tablet first the way its label says, then wait at least 30 minutes before Liao.
Will Liao affect my weight loss on a GLP-1?
No. It's a digestive formula, not an appetite product. It doesn't change what your GLP-1 does.
Does it help with GLP-1 sulfur burps and bloating?
Yes. Less burping and less bloating are usually the first things people notice, in the first week.
How fast does it work?
You'll feel it soothe from the first spoon. The nights build over the first few weeks. That's why I recommend the 3-month plan.
What does it taste like?
Mild licorice tea. It's a thick syrup, so take it straight off the spoon or stir it into warm water.
What if it doesn't work for me?
You get your money back. 30 days, no questions.
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- Carried by 50+ practitioners
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Start your GLP-1 reflux plan
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Keep your GLP-1. Get your nights back.
Dr. Lyda Kermani, DACM, LAc
This is an advertisement for Liao. Liao is a dietary supplement. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Keep taking your prescribed medication as directed and talk to your prescriber about any supplement you add. Contains licorice root; if you have high blood pressure, talk to your doctor first.
Ozempic®, Wegovy® and Rybelsus® are registered trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. Liao is not affiliated with either company.